The Definitive Guide to ceesdekker
The Definitive Guide to ceesdekker
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Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transportation of macromolecules
Dynamics of initiation, termination and reinitiation of DNA translocation via the motor protein EcoR124I
Because 2000, Dekker has shifted the leading focus of his perform toward biophysics where he reports the Attributes of single biomolecules and cells using the equipment of nanotechnology. This modification of field was driven by his fascination for that remarkable functioning of biological molecular constructions, together with via the lengthy-phrase point of view a large number of attention-grabbing discoveries may be expected On this discipline.[five] Latest strains of investigate in his biophysics team are inside the areas of:[six]
2012, discovery that nucleoid occlusion underlies the precision of bacterial cell division; and to start with ever research of your dynamics DNA supercoils and the discovery of supercoil hopping
Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of only one wire bridging two electrodes
You're a Christian. If you may make such a artificial mobile, would you be just one stage nearer to God, or would the part of God have diminished somewhat yet again?
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2003, shown the main biosensors built outside of a carbon nanotube; solved the framework and mechanism of DNA restore proteins; and discovery of a brand new technique for fabricating good-condition nanopores for DNA translocation
1). The present–voltage curves confirmed considerable modulations with gate voltage, even at room temperature, which was per band bending inside a ~0.six eV bandgap semiconducting nanotube. These information cees dekker also confirmed which the conductance could be modulated by six orders of magnitude by altering the gate voltage. The effects of this operate — a home-temperature transistor made out of only one carbon nanotube molecule — had been released in Nature in Could 1998.
Because 2000 he moved to one-molecule biophysics and nanobiology, with analysis from scientific studies of DNA loop extrusion and supercoiling to DNA translocation as a result of nanopores. Much more a short while ago his investigation has focused on researching chromatin construction and mobile division with germs on chip, though he is additionally attempting to in the end Make synthetic cells from The underside up.
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Instance (two) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is demonstrated in grey, the rim on the pore is highlighted in red, plus a 3D rendering of the motion of your DNA rod is shown.